Fertility & IVF 5 min read • February 04, 2026
IVF with PGT-A Genetic Screening: Maximizing Clinical Pregnancy Rates in 2026
D
Dr. Sunita Mukherjee, DGO
Lead Consultant - Reproductive Medicine
Why PGT-A Screening Changes IVF Outcomes
Chromosomal aneuploidy is the leading cause of embryo implantation failure and early first-trimester miscarriages. By biopsying a few trophectoderm cells on Day 5/6 blastocysts, next-generation sequencing (NGS) screens for all 24 chromosomes prior to frozen embryo transfer.
Who Benefits Most from PGT-A?
- Women aged 35 and older with declining egg chromosomal fidelity.
- Couples with two or more previous unexplained IVF implantation failures.
- Couples experiencing recurrent early pregnancy loss.
- Patients seeking single embryo transfer (eSET) to avoid multiple gestation risks.